C01 – Electro-physical stimulation of osseoinduction via alloplastic osteosynthesis system after ablative surgery in the mandible

Summary of the work programme

The project will explore electrical stimulation of bone using active osteosynthesis systems with the aim to reconstruct critical-size defects of the mandibular bone. After establishment of electrical stimulation parameters to improve growth of stem cells and preliminary animal experiments, these findings concerning electrical stimulation of osseous tissue will now be translated into coordination of conception and design of a load-bearing electrically active osteosynthesis system. In order to further improve the current implant system model, coating of the titanium surface with a dielectric ceramic with piezoelectric properties seems promising as it could be additionally used as a transducer of electrical current.

Cooperation projects

A02 / A04 / B01 / B03 / B05 / B06 / B07 / C02 / S01

 

Staff

Laura Lembcke
Joelle Wachsmann
Dr. Mohamed Elhensheri (finished)

Associated staff

PD Dr. Nadja Engel
Dr. med. Diana Heimes

Fellowship holders

Iliana Mechkarova (finished)