A05 - Dielectric characterisation of cells, tissues and materials

Summary of the work programme

The dielectric properties of cells and tissues determine their response to electrical stimulation. Electrical characteristics will be investigated in project A05 by dielectric spectroscopy. The initial objectives are the description of trabecular bone, the evaluation of electrode interfaces, including coatings, and the assessment of bone cell growth on surfaces. The goal is to eventually develop dielectric measurements towards a non-invasive method that allows monitoring of the integration of implants with respect to patient-specific differences. Future work also aims to apply methods and procedures towards other tissue types, such as cartilage, and the detailed assessment of stimulation parameters with respect to the development of exposed cells.

Cooperation projects

A02 / A03 / B01 / B05 / C02

Publications

2019

Shi, Fukun; Zhuang, Jie; Kolb, Juergen F. (2019): Discrimination of different cell monolayers before and after exposure to nanosecond pulsed electric fields based on Cole–Cole and multivariate analysis. In: Journal of Physics D: Applied Physics 52 (49), S. 495401. DOI: 10.1088/1361-6463/ab40d7.
 

2018

Shi, Fukun; Steuer, Anna; Zhuang, Jie; Kolb, Juergen F. (2018): Bioimpedance Analysis of Epithelial Monolayers after Exposure to Nanosecond Pulsed Electric Fields. In: Transactions on Biomedical Engineering. DOI: 10.1109/TBME.2018.2882299.

Talks

2019

Kolb, Juergen F. (2019): Dielectric and Electrical Properties of Porcine Femur fitted with CPE Element and Cole Model. 13th International Workshop on Impedance Spectroscopy. Chemnitz, Germany, September 2019.

Kolb, Juergen F.; Steuer, Anna; Wolff, Christina M.; Shi, Fukun; Schmidt, Anke; Wende, Kristian et al. (2019): Collective manipulation of cells in monolayers by pulsed electric fields and non-thermal plasma. 3rd World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine, and Food & Environmental Technologies. Toulouse, France, September 2019.

Steuer, Anna; Shi, Fukun; Wolff, Christina M.; Kolb, Juergen F. (2019): Pulsed electric fields for the manipulation of cancer cells. Hauptvortrag. Frühjahrstagung der Deutsche Physikalische Gesellschaft. Munich, Germany, March 2019.
 

2018

Kolb, Juergen F. (2018): The Application of Nanosecond Pulsed Electric Fields on Cancer Therapy: A Study based on Dielectric Characteristics. 19th Asian Conference on Electrical Discharge. Xi’an, China, November 2018.

Kolb, Juergen F. (2018): Applications of Bioelectrics: Dielectric Characterization. 7th East Lake International Forum for Outstanding Overseas Young Scholars. Wuhan, China, December 2018.
 

2017

Kolb, Juergen F. (2017): Bioimpedance Analysis of Epithelial Monolayer after Exposure to Nanosecond Pulsed Electric Fields (nsPEFs). 2nd World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine and Food & Environmental Technologies. Norfolk, United States of America, September 2017.

Kolb, Juergen F. (2017): Applications of Graphene on the Surface Modification of Implant Materials. 29th Annual Conference des Gesellschaft Chinesischer Chemiker und Chemieingenieure in der Bundesrepublik Deutschland e.V. - 17th Parallel Forum Central Indiana Educational Service Center Annual Meeting. Hamburg, Germany, October 2017.

Posters

2018

Kolb, Juergen F. (2018): Bioimpedance Spectroscopy to Distinguish Non-malignant and Malignant Cells before and after Exposure to Nanosecond Pulsed Electric Fields. 12th International Workshop on Impedance Spectroscopy. Chemnitz, Germany.

Project leader

Prof. Dr. rer. nat. Jürgen F. Kolb
E-Mail
Tel.: +49 3834 554 3950

Institution

Leibniz Institute for Plasma Science and Technology
Felix-Hausdorff-Str. 2
17489 Greifswald

Staff

Wenzuo Wei

Associated staff

Fukun Shi