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Project groups and projects

Knowledge transfer from project area to the consortium

From A01 to

A02:
Properties about the morphology of the cell, and the heterogeneity of the cell population
A02:
Specification and integration of simulation experiments and simulation studies into workflows
A03:
Models and simulation studies: membrane dynamics, signalling pathways, and migration
C01:
Models and simulation studies: signalling pathways, cell differentiation (osteoprogenitors), interaction
C04:
Models and simulation studies: signalling pathways, cell differentiation (neurogenesis), interactions
A:
Domain-specific languages to specify and discuss models and simulation studies
C:
Domain-specific languages to specify and discuss models and simulation studies

From A02 to

A:
Theoretical models, numerical micro- and macro-scale simulation models, electric field distributions
A01:
Description of and information about simulation experiments, and simulation studies
B01:
Modelling of the piezoelectric effect and the resulting stimulation effect in/of the 3D-printed scaffolds
B02:
Electrode positioning for optimal stimulation
B03:
Multi-scale simulation models and exchange on stimulation methods
B03:
Macroscopic simulation results and exchange on stimulation methods
B04:
Simulation results regarding deep brain stimulation
B05:
Macroscopic electric field simulation results for integration into mechanical models
C:
Implant/electrode design, in particular application-specific stimulation duration, frequency and shape
C01:
Design of the osteosynthesis screws and plates, simulation of the required parameters
C02:
Microscopic simulation models for combined or single mechano-electrical stimulation
C02:
Modelling of the piezoelectric effect and the resulting stimulation effect in/of the 3D-printed scaffolds
C03:
Definition of realistic stimulation parameters
C03:
Modelling the volume of tissue activated within basal ganglia (entopeduncular nucleus)
C03:
Galvanotaxis - modelling and simulation within the teaching projects on research-oriented learning
C04:
Modelling the volume of tissue activated within brain tissue (basal ganglia)
C:
Multi-scale simulation models including uncertainty quantification (long-term goal)

From A03 to

A01:
Hypothesis, data for analysing the impact of electrical fields on cell functions
A02:
Insights in surface processes as input for model parameters into micro-scale models
A02:
Validation of simulation results
A04:
Varying zeta-potentials on implant surface
B01:
Findings about processes on bioactive, piezoelectric implant structures
B05:
Identification of optimum surface structure considering the implant's fatigue strength
C01:
Principles of osteoblast adhesion to osteosynthesis-surfaces, identification of cellular effects
C02:
Cultivation of stem cells in scaffolds

From A04 to

A02:
Insights in surface processes as input for model parameters into micro-scale models
A02:
Validation of simulation results
A03:
Large flat surfaces with electrically conductive nm-thick films for electric stimulation of osteoblasts
A03:
Surfaces of different chemical composition and charge for osteoblast adhesion
C04:
Large flat surfaces with electrically conductive nm-thick films for electric stimulation of neurons