A04 - Electrically conductive multilayer films for implant surfaces

Summary of the work programme

To understand and eventually to control the reaction of cells to electro-stimulation, many cells are to be exposed simultaneously to the same time-dependent electric field. Cells will grow on large (centimetre-squared) flat surfaces, which will be functionalised with ultrathin electrically conductive, multilayer films. These films are prepared by sequential adsorption of oppositely charged macromolecules and electrically conductive nanoparticles, with the adsorption sequence of the different composites determining the properties of each film.

Cooperation projects

A02 / A03 / C04

Publications

Heba S. Mohamad, Sven Neuber, Christiane A. Helm: Surface Forces of Asymmetrically Grown Polyelectrolyte Multilayers: Searching for the Charges,  Langmuir 2019. September 2019. doi.org/10.1021/acs.langmuir.9b01787

Sebastian Runde, Heiko Ahrens, Frank Lawrenz, Amal Sebastian, Stephan Block and Christiane A. Helm: Stable 2D Conductive Ga/Ga (OxHy) Multilayers with Controlled Nanoscale Thickness Prepared from Gallium Droplets with Oxide Skin. Advanced Materials Interfaces, June 2018. doi.org/10.1002/admi.201800323

Peter Nestler and Christiane A. Helm: Determination of refractive index and layer thickness of nm-thin films via ellipsometry. Optics Express, volume 25 (22): pages 27077-27085, October 2017. doi.org/10.1364/OE.25.027077

Conference papers

Nebe J.Barbara, Martina Grüning, Henrike Rebl, Birgit Finke, Christiane Helm, Matthias Schnabelrauch, Katja Fricke, and Susanne Staehlke: Complex cell physiology on chemically and topographically designed implant surfaces. Invited keynote lecture; 3rd International Conference on Dentistry and Oral Health (ICDO 2019), September 2019, London, UK.

Martina Gruening, Henrike Rebl, Susanne Staehlke, Birgit Finke, Sven Neuber, Christiane Helm and Barbara Nebe: Polyelectrolyte multilayers on titanium and their influence on osteoblast behavior. 9th International Congress, Nanotechnology in Biology Medicine, April 2018, Graz, Austria.

Annkatrin Sill, Amir Azinfar, Sven Neuber, Peter Nestler and Christiane A. Helm: Molecular properties and growth conditions associated with PSS diffusion during annealing in polyelectrolyte multilayers, CPP: Fachverband Chemische Physik und Polymerphysik, March 2018, Berlin, Germany.

Heba Soker Mohamad, Sven Neuber and Christiane A. Helm: How to tune the surface forces of PDADMA terminated polyelectrolyte multilayers, CPP: Fachverband Chemische Physik und Polymerphysik, March 2018, Berlin, Germany.

Peter Nestler, Malte Paßvogel, Annekatrin Sill, Amir Azinfar and Christiane A. Helm: Annealing in polyelectrolyte multilayers: influence of entanglements, Institute of Physics and Biophysics and the Institute of Chemistry and Biochemistry, Faculty of Science, University of South Bohemia, Czech Republic.

Posters

Heba S. Mohamad, Sven Neuber, Christiane A. Helm: Surface forces of asymmetrically grown polyelectrolyte multilayers: searching for the charges. Nano-Bio-Physics Symposium 2019: “Stretching the boundaries of physics, one molecule at a time” September 2019, Munich, Germany.

Martina Gruening, Jutta Lehnfeld, Rainer Mueller, Katja Fricke, Sven Neuber, Christiane Helm, Manuela Dubs, Matthias Schnabelrauch, Barbara Nebe: The role of material’s zeta potential on intracellular calcium ion signaling. 4th European Symposium on Intelligent Materials, June 2019, Kiel, Germany - Poster Award 2019

Martina Gruening, Jutta Lehnfeld, Rainer Mueller, Katja Fricke, Sven Neuber, Christiane Helm, Manuela Dubs, Matthias Schnabelrauch, Barbara Nebe: Material surface charges and their influence on cell physiology. 6th International Symposium Interface Biology of Implants, May 2019, Warnemünde, Germany.

Heba S. Mohamad, Sven Neuber, Annekatrin Sill and Christiane A. Helm: A wide Range of Surface Forces of PSS terminated Polyelectrolyte Multilayers, DPG (Deutsche Physikalische Gesellschaft) - Frühjahrstagung, March 2019, Regensburg, Germany.

Martina Grüning, Henrike Rebl, Susanne Stählke, Birgit Finke, Sven Neuber, Christiane A. Helm and Barbara Nebe: Biomaterial surface charges and their influence on cell signaling in living osteoblasts, ESB2018: Accepted abstract at 29th European Conference on Biomaterials, September 2018, Maastricht, Netherlands.

Amir Azinfar, Sven Neuber, Jiří Vaněček, Marie Vancová, Jan Sterba, Vítězslav Straňák and Christiane A. Helm: Roughness and Salt Annealing of a Polyelectrolyte Multilayer, DPG (Deutsche Physikalische Gesellschaft) - Frühjahrstagung, March 2018, Bad Honnef, Germany.

Peter Nestler, Malte Paßvogel, Annekatrin Sill, Amir Azinfar and Christiane A. Helm: Annealing in polyelectrolyte multilayers: influence of entanglements, DPG (Deutsche Physikalische Gesellschaft) -Frühjahrstagung, March 2017, Dresden, Germany.

Project leader

Prof. Dr. rer. nat. habil. Christiane A. Helm
E-Mail
Tel.: +49 3834 420 4710

Institution

University of Greifswald
Institute of Physics
Felix-Hausdorff-Str. 6
17489 Greifswald