Peer-reviewed journal articles 2022

Bornemann A, Franz D, Engel N, Heerdegen M, Kragelund FS, Lüttig A, Perl S, Plocksties FV, Richter A, Köhling R (2022) Analysis of gene expression changes in the cerebellum after pallidal deep brain stimulation in the animal model of the dystonic dt(sz) mutant. Acta Physiologica 236, pp.835-837

Panagiotopoulos I, Starke J, Just W. Control of collective human behavior: Social dynamics beyond modeling, Phys. Rev. Research 4, October 2022,

Sahm F, Jakovljevic A, Bader R, Detsch R, Jonitz-Heincke A. Is There an  Influence of Electrically Stimulated Osteoblasts on the Induction of  Osteoclastogenesis? Applied Sciences. 2022; 12(22):11840.

Becker S, Schulz A.; Kreyer S.; Dreßler J., Richter A, Helmschrodt C. Sensitive and simultaneous quantification of 16 neurotransmitters and metabolites in murine microdialysate by fast liquid chromatography-tandem mass spectrometry. Talanta. 2022 Sep 24;253:123965. doi: 10.1016/j.talanta.2022.12396

Perl S, Lüttig A, Köhling R, Richter. Deep brain stimulation in animal models of dystonia: opportunities and limitations. Neurobiology of Disease,

Weizel, A.; Distler, T.; Detsch, R.; Boccaccini, A.R.; Bräuer, L.; Paulsen, F.; Seitz, H.; Budday, S.: Hyperelastic parameter identification of human articular cartilage and substitute materials. Journal of the Mechanical Behavior of Biomedical Materials. 133 (2022) 105292 DOI: 10.1016/j.jmbbm.2022.105292

Kara, A., Distler, T., Polley, C., Schneidereit, D., Seitz, H., Friedrich, O., ... & Boccaccini, A. R. 3D printed gelatin/decellularized bone composite scaffolds for bone tissue engineering: Fabrication, characterization and cytocompatibility study. Materials Today Bio, 2022, 100309.

Spiliotis K, Koutsoumaris CC, Reppas AI, Papaxenopoulou LA, Starke J, Hatzikirou H. Optimal vaccine roll-out strategies including social distancing for pandemics, iScience, Volume 25, Issue 7, 2022, .

Spiliotis, K,  Butenko K, Starke J, van Rienen U, Köhling R. Complex network measures reveal optimal targets for deep brain stimulation and identify clusters of collective brain dynamics. Front. Phys. 2022, doi: 10.3389/fphy.2022.951724

Voelkner C, Assi I, Karberg W, Lange R, Neuber S, Helm CA, Gruening M, Nebe JB, Barke I, Speller S. Response of Osteoblast Adhesion to Electric Field Line Patterns Emerging from Molecule Stripe Landscapes. Applied Sciences, 2022, 12(14), 7329,

Jonathan Edward Dawson, Tina Sellmann, Katrin Porath, Rainer Bader, Ursula van Rienen, Revathi Appali and Rüdiger Köhling, Cell-cell interactions and fluctuations in the direction of motility promote directed migration of osteoblasts in direct current electrotaxis, Front. Bioeng. Biotechnol. 10:995326. doi: 10.3389/fbioe.2022.995326.

Gellert, F., Ahrens, H., Wulff, H., and Helm C.A..(2022). Seaweed and Dendritic Growth in Unsaturated Fatty Acid Monolayers. In the special issue: “Model Lipid Membrane” in the section: “Biological Membrane Dynamics and Computation”. Membranes 12 (7) 698. DOI: 10.3390/membranes12070698.

Runde, S., Ahrens, H., Wulff, H., & Helm, C.A. (2022): Stable Metal/Metal Hydroxide Multilayers with Controlled Nanoscale Thickness Prepared from Liquid Metal Droplets withOxide Skin. The Journal of Physical Chemistry C 126 (27) 11254–11264. DOI:10.1021/acs.jpcc.1c10780.

Sahm F, Grote VF, Zimmermann J, Haack F, Uhrmacher AM, van Rienen U, Bader R, Detsch R, Jonitz-Heincke A. Long-term stimulation with alternating electric fields modulates the differentiation and mineralization of human pre-osteoblasts. Frontiers in Physiology, section Skeletal Physiology. (2022).

Bielfeldt M, Rebl H., PetersK, Sridharan K,  Staehlke S, Nebe B. Sensing of Physical Factors by Cells: Electric Field, Mechanical Forces, Physical Plasma and Light—Importance for Tissue Regeneration.Biomedical Materials & Devices (2022).

Staehlke S, Bielfeldt M, Zimmermann J, Gruening M, Barke I, Freitag T, Speller S, van Rienen U, Nebe B. (2022): Pulsed Electrical Stimulation Affects Osteoblast Adhesion and Calcium Ion Signaling, Cells, 11, 2650.

Wilsdorf P, Heller J, Budde K,Zimmermann J, Warnke T, Haubel C, Timmermann D, van Rienen U, Uhrmacher AM. (2022): A Model-Driven Approach for Conducting Simulation Experiments, Appl. Sci.2022, 12(16), 7977;

Lee PS, Heinemann C, Zhen K, Appali R, Alt F, Krieghoff J, Bernhardt A, Boccaccini AR, van Rienen U, Hintze V. (2022): The interplay of collagen/bioactive glass nanoparticle coatings and electrical stimulation regimes distinctly enhanced osteogenic differentiation of human mesenchymal stem cells, Acta Biomaterialia, DOI: 10.1016/j.actbio.2022.06.045

Ruscheinski A, Wilsdorf, P, Zimmermann J, van Rienen U, Uhrmacher ,Adelinde M. (2022): An Artifact-based Workflow for Finite-Element Simulation Studies. Simulation Modelling Practice and Theory, 116, p. 102464. ISSN 1569-190X. DOI: 10.1016/j.simpat.2021.102464

Zimmermann J, Altenkirch R, van Rienen U. (2022). Numerical study on the effect of capacitively coupled electrical stimulation on biological cells considering model uncertainties. Scientific Reports, 12, 4744. DOI: 10.1038/s41598-022-08279-w

Saemann M , Darowski M, Hennicke N S, Bader R, Sander M, Kluess D. Experimental analysis of early periprosthetic femoral fractures with uncemented straight hip stems. Clinical Biomechanics 91 (2022): 105543. DOI: 10.1016/j.clinbiomech.2021.105543

Neuber S, Sill, A Efthymiopoulos I, Nestler P, Fricke K, & Helm C A (2022). Influence of molecular weight of polycation polydimethyldiallylammonium and carbon nanotube content on electric conductivity of layer-by-layer filmsThin Solid Films, 139103, DOI: 10.1016/j.tsf.2022.139103.

Schröder M, Staehlke S, Groth P, Nebe JB, Spors S, Krüger F. Structure-based knowledge acquisition from electronic lab notebooks for research data provenance documentation. J Biomed Semantics. 2022 Jan 31;13(1):4. doi: 10.1186/s13326-021-00257-x.

Schindler D, Bensmann F, Dietze S, Krüger F. The Role of Software in Science: A Knowledge Graph-Based Analysis of Software Mentions in PubMed Central. 2022. PeerJ Computer Science 8 (January): e835.

Polley C, Radlof W, Hauschulz F, Benz C, Sander M, Seitz H. Morphological and mechanical characterisation of three-dimensional gyroid structures fabricated by electron beam melting for the use as a porous biomaterial. J Mech Behav Biomed Mater. 2022 Jan;125:104882. doi: 10.1016/j.jmbbm.2021.104882

Andree A, Li N, Butenko K, Kober M, Chen JZ, Higuchi T, Fauser M, Storch A, Ip CW, Kühn AA, Horn A, van Rienen U. Deep brain stimulation electrode modeling in rats. Exp Neurol. 2022 Apr;350:113978. doi: 10.1016/j.expneurol.2022.113978 . Epub 2022 Jan 11. PMID: 35026227.

Wei W, Shi F, Kolb JF, Analysis of microstructural parameters of trabecular bone based on electrical impedance spectroscopy and deep neural networks, Bioelectrochemistry 148 (2022) 108232 (10pp). doi:10.1016/j.bioelechem.2022.108232 

Butenko, K., & van Rienen, U. (2022). DBS imaging methods III: Estimating the electric field and volume of tissue activated. In Connectomic Deep Brain Stimulation (pp. 147-168). Academic Press. DOI: 10.1016/B978-0-12-821861-7.00021-X.

Peer-reviewed conference papers 2022

Plocksties, F.; Lüttig, A.; Niemann, C.; Uster, F.; Franz, D.; Kober, M.; Koschay, M.; Perl, S.; Richter, A.; Köhling, R.; Storch, A.; Timmermann, D., Strategies on Deep Brain Stimulation Devices for Effective Behavioral Studies in Rodents, In Proceedings of the IEEE-EMBS Conference on Biomedical Engineering and Sciences (IECBES), Kuala Lumpur, Malaysia, Dezember 2022.

Koschay, M.; Richter, H.; Statz, M.; Kober, M.; Puschmann, J.; Plocksties, F.; Storch, A.; Kühn, V.; Timmermann, D., Case-Study on Visible Light Communication for Implant Monitoring, In Proceedings of the IEEE Biomedical Circuits and Systems Conference (BioCAS), Taipeh, Taiwan, Oktober 2022. DOI: 10.1109/BioCAS54905.2022.9948625

H. Bathel, L.V. Che, J. Zimmermann, A. Weizel, H. Seitz, U. van Rienen. Electrical impedance spectroscopy on capacitively coupled electrodes for cartilaginous cell stimulation. International Workshop on Impedance Spectroscopy (IWIS), 27-30 September 2022, Chemnitz, Germany. 

Radlof, Wiebke; Panwitt, Hannes; Benz, Christopher; Sander, Manuela (2022). Image-based and in-situ measurement techniques for the characterization of the damage behavior of additively manufactured lattice structures under fatigue loading. Procedia Structural Integrity 38 (2022) 50–59. DOI:

Lisa Krukewitt, Sascha Spors, Karl Völzer, Rainer Bader, and Daniel Klüß. Detecting hip-stem implant loosening by deep anomaly detection using structure borne sound. In German Annual Conference on Acoustics (DAGA), March 2022.

Abstracts 2022

Wanda Witte, Christian Völkner, Regina Lange, Susanne Seemann, Barbara Nebe, Ingo Barke, and Sylvia Speller: The zeta potential as parameter in electric field landscapes for guiding cell adhesion. DPG spring conference 2022, Regensburg

Franziska Dorn, Christian Völkner, Meike Genzow, Martina Grüning, Sven Neuber, Regina Lange, Ingo Barke, Christiane A. Helm, Barbara Nebe, and Sylvia Speller: Electrostimulation of osteoblasts on coated planar resistive electrodes. DPG spring conference 2022, Regensburg
Lukas Böttcher, Anna Dittus, Jens Starke, Ingo Barke, and Sylvia Speller. Inspecting non-linearities in scanning force microscopy. DPG spring conference 2022, Regensburg

W. Radlof, H. Rebl, C. Polley, H. Seitz, J.B. Nebe, M. Sander. Functionally graded gyroid structures fabricated by electron beam melting: Mechanical behavior and cell occupation.7th CellMat, Dresden 2022.

Meike Genzow, Nikolai Weis, Kai Budde, Susanne Stählke, Adelinde Uhrmacher, Barbara Nebe: Impact of alternating current stimulation on osteoblasts’ ROS production – direct contact vs. AC-conditioned liquids. BMT 2022 – Joint Annual Meeting of the Austrian, German and Swiss Societies for Biomedical Engineering including the “14th Vienna International Workshop on Functional Electrical Stimulation”, September 28th to 30th Innsbruck, Austria. 

Genzow M, Stählke S, Sridharan K, Waldner A, Rebl H, Peters K, Nebe B: Impact of physical forces on cell physiology for tissue regeneration. Deutsche Gesellschaft für Biomaterialien (DGBM), Essen 2022/09

Meike Genzow, Julius Zimmermann, Thomas Freitag, Ulla van Rienen, J. Barbara Nebe, Susanne Staehlke: Influence of low frequency electrical stimulation on osteoblast growth: Cellular effects via AC-conditioned liquids. ESB 2022, Bordeaux Sep 2022.

Jan Philipp Payonk, Ursula van Rienen, Revathi Appali. Pathway activation models for deep brain stimulation of rodents. Accepted as oral presentation for Virtual Physiological Human (VPH) Conference, 6-9 September 2022, Porto.

Hendrikje Raben, Peer W. Kämmerer, Michael Dau, Ursula van Rienen. Numerical model of an electrically stimulated minipig lower jaw considering model uncertainties. Submitted as oral presentation for workshop “Zuverlässigkeit von Implantaten und Biostrukturen” of Deutscher Verband für Materialforschung und -prüfung e.V. (DVM), 29-30 September 2022, Rostock.

Anna Fontes Gomes, Ursula van Rienen and Revathi Appali, Challenges in Multiscale Modeling of Electrically Active Bone Implants. Submitted to Zuverlässigkeit von Implantaten und Biostrukturen Conference, 29-30 September 2022.

Anna Fontes Gomes, Ursula van Rienen and Revathi Appali, Multiscale modeling in the context of electric active implants. Accepted to Virtual Physiological Human (VPH) Conference, 6-9 September 2022, Porto.

Publications of the SFB 1270/2 ELAINE on:


» Funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) – SFB 1270/2 - 299150580 «