A03 – Electrostimulation-induced cellular responses: Biomarkers for eustress levels and model implant surfaces

Summary of the work programme

The aim is to elucidate the interactions between cells (osteoblasts, stem cells) and electrical stimulation in combination with innovative material scaffolds. Detailed investigations will focus on cell physiological processes at the cell-material interface in 2D and 3D cultures, the structural and piezoelectric properties of the material surface, and their influence on cell behaviour, including calcium signalling and protein translocation, which affect cell morphology. High-resolution scanning probe microscopy methods are combined with cell biological analyses to gain a thorough understanding of these complex interactions.

Cooperation projects

A02 / A04 / A05 / A06 / B01 / C02 / C03 / S01 / INF

Project leader

Dr. rer. nat. Henrike Rebl
E-Mail
Tel: +49 381 494 7771

Prof. Dr. rer. nat. habil. Sylvia Speller
E-Mail
Tel: +49 381 498 6980

Institutions

Rostock University Medical Center
Institute of Cell Biology​
Schillingallee 69
18057 Rostock

University of Rostock
Institute of Physics
Albert-Einstein-Straße 23 - 24
18059 Rostock

Staff

Franziska Dorn
E-Mail

Associated staff

Dr. Ingo Barke
E-Mail

Regina Lange
E-Mail

Dr. Susanne Stählke
E-Mail

Former staff

Katharina Engster
Dr. Martina Grüning
Dr. Susanne Seemann
Max Ulbrich
Christian Völkner