The SFB 1270/2 "Electrically active implants - ELAINE" involves about 70 scientists from the fields of electrical engineering, computer science, mechanical engineering, material sciences, physics, mathematics, biology and medicine.
The following lecture series will also take place in the 2nd funding period:
"Women in Natural Sciences and (Bio-)Engineering"
This time, the series is organized together with the SFB 1477 LiMatI. The lectures will be held 1-2 per month on Fridays at 2 p.m.
With this lecture series, we would like to provide insights into the everyday professional life of successful female scientists and exciting answers to questions about individual decision-making processes for a life path in STEM fields. STEM is an acronym for the fields science, technology, engineering, and mathematics and is a broad term used to group together these academic disciplines.
Of course, the lecture series is not only addressed to girls and young women - the career path and scientific topics will be interesting for all knowledge-thirsty people.
When: during the semester, Friday 2 - 3 p.m.
Where: hybrid (via Zoom), Hörsaal Ex04, Experimentalgebäude, Albert-Einstein-Str. 2 (Südstadt-Campus)
Winter semester 2022/23
Dr.-Ing. Silvia Budday, Institute of Applied Mechanics, Friedrich-Alexander-Universität Erlangen
23.11.2022 -ELAINE Colloquia
Prof. Sarah Cartmell, University of Manchester
Prof. Annemie Bogaerts, University of Antwerp, Department of Chemistry
CO2 activation with light - is it possible?
Prof. Stefanie Tschierlei, Physical Chemistry, TU Braunschweig
Due to the excessive use of carbon-based raw materials for energy production, the greenhouse effect is inexorably increasing. The reduction of CO2, one of the most common anthropogenic greenhouse gases, into more synthetically usable C1 building blocks is therefore highly desirable. A sustainable method for conversion is photocatalysis with suitable photoactive substances. Such a system was developed as early as 1983 by Lehn et al. based on (bpy)Re(CO) 3 Cl (bpy = 2,2'-bipyridine).
We recently discovered an unexpected wavelength dependency of this well-known (bpy)Re(CO)3Cl complex. Irradiation with wavelengths >450 nm triggers an alternative reaction pathway involving a dimeric Re-Re species and results in an increased catalytic activity during the photocatalytic CO2 reduction. Inspired by these results we designed a dinuclear rhenium complex with closely oriented metal centers. The presented study aims on the elucidation of possible reaction mechanism. Therefore, time-dependent catalytic and spectroscopic experiments as well as UV/vis and IR spectroelectrochemical measurements accompanied by TD-DFT calculations were performed.
Stefanie Tschierlei is a full professor (W3) at the Institute for Physical and Theoretical Chemistry and head of the Department of Energy Conversion at the TU Braunschweig. ST studied chemistry at the Friedrich-Schiller-Universität in Jena from 2002 to 2006. After finishing her dissertation in 2010 with summa cum laude she received a DAAD scholarship for a postdoc stay at the Department of Photochemistry and Molecular Science at the Uppsala University in Sweden. She then worked as a researcher at various universities, including Rostock, Stuttgart and Ulm before she was appointed as a professor in August 2020. Since 2022 she is the chairwoman of the GDCh division of photochemistry. Her research is mainly engaged in the spectroscopic and mechanistic study of light-driven processes for (solar) energy conversion, e.g. the splitting of water or the reduction of CO2.
How can musculoskeletal research in space help to develop the next generation of active orthopedic implants?
Prof. Bergita Ganse, Kliniken und Institute für Chirurgie, Universität des Saarlandes
Bergita’s research ranges from basic research on musculoskeletal changes in microgravity, to surgery in spaceflight, immobilisation and fracture healing, to clinical research in orthopaedic trauma surgery. Her main research focus is the musculoskeletal system in spaceflight and in immobilisation. Most of the research is conducted together with DLR, ESA and NASA, involving bed rest studies, experiments on board the International Space Station and in Antarctica. With her group at Saarland University, she runs Orthopaedic Trauma Surgery research projects that deal with injury, implant development, fracture healing and biomechanics. Bergita likes to combine research in space with clinical research and to translate the knowledge gained in the space context for the benefit of the patients here on Earth.
Bergita Ganse is a full professor (W3) and head of the Werner Siemens Foundation Endowed Chair for Innovative Implant Development (Fracture Healing) at Saarland University in Germany and a visiting professor at Manchester Metropolitan University in the UK. She is a medical doctor specialized in orthopaedic surgery and physiology, and has completed subspeciality trainings in emergency medicine and sports medicine. Bergita has previously worked at Charité-University Medicine Berlin, Cologne University Hospital, the German Aerospace Center DLR, RWTH Aachen University Hospital (all Germany) and completed a 2-year research fellowship at Manchester Metropolitan University in the UK before she became a full professor in March 2021.
Cellular response to wear and corrosion products
Dr. Anika Jonitz-Heincke, Leiterin Geweberegeneration, Orthopädische Klinik und Poliklinik, Universitätsmedizin Rostock
A comprehensive understanding of wear-induced osteolysis is a prerequisite for developing new preventive or therapeutic approaches that can delay or prevent the progression of osteolysis and the associated implant loosening. In this context, toxicity analyses at the cellular level allow the identification of the specific biological response to wear and corrosion products. Macrophages are reported to be the crucial cell type with regard to the inflammatory event and bone resorption, as these cells are able to phagocytose wear products and release inflammatory mediators in response. In contrast, few studies have indicated that, in addition to macrophages, osteoblasts and fibroblasts are also capable of uptaking wear debris. Therefore, in order to obtain a comprehensive cellular response to wear products, different cell types need to be considered to provide further methodological perspectives for the risk assessment of established and novel implant materials.
Anika Jonitz-Heincke is a scientific researcher in the Research Laboratory of Biomechanics and Implant Technology of the Department of Orthopaedics since 2009. She has managed the tissue regeneration research group since 2012 and in 2016 she became deputy head of the laboratory. AJH completed both her PhD in 2014 and her Habilitation in 2022 in the field of Experimental Orthopedics. Her research interests include various aspects of musculoskeletal tissue regeneration, particularly biophysical stimulation of bone and cartilage tissue, cell-material interaction, and biotribological issues.
Cell physiology and tissue regeneration – Physical plasma in BioMedicine
Prof. Dr. Barbara Nebe, Arbeitsbereich Zellbiologie, Universitätsmedizin Rostock
Plasma medicine and plasma biology has become an important area of interdisciplinary research in plasma physics, combining biology, chemistry and physics. The fields of application of physical plasma in biomedicine are increasing and include the direct influence of physical plasma on cells and tissues or the biomaterial surface functionalization. Biomaterials should be bioactive in stimulating the surrounding tissue to accelerate the ingrowth of permanent implants. Plasma-chemical modifications are able to boost not only cell attachment, cell migration and differentiation, but also intracellular signaling.
J. Barbara Nebe is an adjunct Professor of Cell Biology, and chair of the Department of Cell Biology in the Rostock University Medical Center. BN received her Ph.D. in 1995, and the Habilitation and venia legendi in 2005 with the theme “Integrin receptors, cell adhesion, and cell signalling – clinical aspects”. She is focused on cell biological issues in interfacial interactions of the biosystem to implant surfaces, and the impact of physical factors on cell physiology. She is experienced in cross-disciplinary research and project leader of several DFG projects. BN was invited speaker, e.g. in Paris (THERMEC), Ambleteuse (BIOMAT), Shanghai (BIT's RMSC), Las Vegas (THERMEC), Singapore (ICMAT). She organised/co-organised 10 international congresses, e.g. ’Functionalised Bio Materials: Therapeutic Applications’ for the European Material Research Society.